TABLE 2.Summary of age-dependent synaptic properties
|
|||||
Property | Age, Days |
||||
P10–P14 (n = 27) | P15–P18 (n = 85) | P19–P29 (n = 37) | |||
|
|||||
Amplitude, mV | 1.0 ± 0.6 | 0.8 ± 0.5 | 0.6 ± 0.4†† | ||
Fail rate | 0.14 ± 0.21 | 0.16 ± 0.19 | 0.25 ± 0.23*† | ||
CV | 0.49 ± 0.24 | 0.60 ± 0.31 | 0.64 ± 0.3† | ||
τd, ms | 44 ± 15 | 37 ± 13** | 24 ± 9**†† | ||
PPR, 10 Hz | 0.68 ± 0.18 | 0.80 ± 0.22** | 0.94 ± 0.20**†† |
Values are means ± SD. CV, coefficient of variation; τd, EPSP decay constant; PPR, paired-pulse ratio. Significance:
** P < 0.01,
* P < 0.05 for adjacent columns (i.e., P10–P14 vs. P15–P18 and P15–P18 vs. P19–P29);
†† P < 0.01,
† P < 0.05 for P10–P14 versus P19–P29.